Gabapentin or pregabalin induced myoclonus: A case series and literature review

@article{Desai2019GabapentinOP,
  title={Gabapentin or pregabalin induced myoclonus: A case series and literature review},
  author={Aaron Desai and Yazan Kherallah and Cheryl Szabo and Rohit Marawar},
  journal={Journal of Clinical Neuroscience},
  year={2019},
  volume={61},
  pages={225-234}
}
Gabapentin (GBP) and pregabalin (PGB) are FDA approved for adjunctive treatment of partial seizures and for treatment of post-herpetic neuralgia. Both drugs are primarily eliminated by renal excretion. However, PGB or GBP induced myoclonus has only been reported infrequently in case reports/series. It is not discussed with patients and its sudden occurrence can lead to anxiety because of "seizure-like" nature. In addition, first-contact physicians might treat it as seizures, leading to… Expand
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