Gabapentin for relief of upper motor neuron symptoms in multiple sclerosis.

  title={Gabapentin for relief of upper motor neuron symptoms in multiple sclerosis.},
  author={Marcio El Ammar M{\"u}ller and Michael Gruenthal and W L Olson and William H. Olson},
  journal={Archives of physical medicine and rehabilitation},
  volume={78 5},
OBJECTIVE To examine the efficacy of gabapentin in the treatment of spasticity and painful muscle spasms in patients with multiple sclerosis. DESIGN Double-blind, placebo-controlled crossover study. SETTING Free-standing, 93-bed, university-affiliated rehabilitation hospital. PARTICIPANTS There were 15 patients between the ages of 18 and 50 who had laboratory-supported definite multiple sclerosis with spasticity and leg cramps severe enough to interfere with daily activities, including… CONTINUE READING

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