Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial

@article{Ryan2012GabapentinFR,
  title={Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial},
  author={Nicole M Ryan and Surinder S. Birring and Peter G Gibson},
  journal={The Lancet},
  year={2012},
  volume={380},
  pages={1583-1589}
}
BACKGROUND Refractory chronic cough causes substantial symptoms and quality-of-life impairment. Similarities between central reflex sensitisation in refractory chronic cough and neuropathic pain suggest that neuromodulators such as gabapentin might be effective for refractory chronic cough. We established the efficacy of gabapentin in patients with refractory chronic cough. METHODS This randomised, double-blind, placebo-controlled trial was undertaken at an outpatient clinic in Australia… CONTINUE READING
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