Gabapentin does not reduce smoked cocaine self-administration: employment of a novel self-administration procedure.

@article{Hart2007GabapentinDN,
  title={Gabapentin does not reduce smoked cocaine self-administration: employment of a novel self-administration procedure.},
  author={Carl L. Hart and Margaret Haney and Suzanne K Vosburg and Eric D Rubin and Richard W. Foltin},
  journal={Behavioural pharmacology},
  year={2007},
  volume={18 1},
  pages={71-5}
}
Previously, we reported that gabapentin, a nonselective gamma-aminobutyric acid agonist, reduced 'positive' subjective effects of cocaine without reducing cocaine self-administration. We speculated that the self-administration procedure used in that study was not sensitive to subtle shifts in the reinforcing effects of cocaine. Thus, this study examined the effects of gabapentin maintenance on cocaine self-administration using a purchase-cocaine choice procedure. During this 48-day inpatient… CONTINUE READING

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