Gabapentin and Pregabalin for the Treatment of Anxiety Disorders

@article{Greenblatt2018GabapentinAP,
  title={Gabapentin and Pregabalin for the Treatment of Anxiety Disorders},
  author={H. Karl Greenblatt and David J Greenblatt},
  journal={Clinical Pharmacology in Drug Development},
  year={2018},
  volume={7}
}
Gabapentin and pregabalin are structurally related compounds which are classified as gammaaminobutyric acid (GABA) analogues or gabapentinoids (Figure 1). Gabapentin, which received American Food and Drug Administration (FDA) approval in 1993, is indicated for the treatment of postherpetic neuralgia, and as adjunctive therapy for refractory partial-onset seizures. It is widely prescribed off-label for diabetic neuropathy and other neuropathic pain conditions. Numerous other off-label and… Expand
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