Gabaergic Control of Spinal Locomotor Networks in the Neonatal Rat

  title={Gabaergic Control of Spinal Locomotor Networks in the Neonatal Rat},
  author={J. Cazalets and S. Bertrand and Y. Sqalli-Houssaini and F. Clarac},
  journal={Annals of the New York Academy of Sciences},
  • J. Cazalets, S. Bertrand, +1 author F. Clarac
  • Published 1998
  • Biology, Medicine
  • Annals of the New York Academy of Sciences
  • Abstract: We studied the GABAergic control of the spinal locomotor network using an isolated brain stem/spinal cord from newborn rats, in which locomotor‐like activity was recorded. We demonstrate that endogenously released GABA controls the locomotor network, by decreasing or completely abolishing all locomotor‐like activity. At first, we investigated the role played by GABA in the control of the locomotor period. By separately superfusing various compartments of the lumbar cord, we identified… CONTINUE READING
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