Gabaergic Control of Spinal Locomotor Networks in the Neonatal Rat

@article{Cazalets1998GabaergicCO,
  title={Gabaergic Control of Spinal Locomotor Networks in the Neonatal Rat},
  author={Jean-Ren{\'e} Cazalets and Sandrine S Bertrand and Youssef Sqalli-Houssaini and François Clarac},
  journal={Annals of the New York Academy of Sciences},
  year={1998},
  volume={860}
}
Abstract: We studied the GABAergic control of the spinal locomotor network using an isolated brain stem/spinal cord from newborn rats, in which locomotor‐like activity was recorded. We demonstrate that endogenously released GABA controls the locomotor network, by decreasing or completely abolishing all locomotor‐like activity. At first, we investigated the role played by GABA in the control of the locomotor period. By separately superfusing various compartments of the lumbar cord, we identified… 
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The overall objective of this thesis is to increase our understanding of neural networks generating locomotion. These networks called Central Pattern Generators (CPG), are localized in the spinal…
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