GXD: a gene expression database for the laboratory mouse. The Gene Expression Database Group

@article{Ringwald1999GXDAG,
  title={GXD: a gene expression database for the laboratory mouse. The Gene Expression Database Group},
  author={Martin Ringwald and Mary E. Mangan and Janan T. Eppig and James A. Kadin and Joel E. Richardson},
  journal={Nucleic acids research},
  year={1999},
  volume={27 1},
  pages={
          106-12
        }
}
The Gene Expression Database (GXD) is a community resource that stores and integrates expression information for the laboratory mouse, with a particular emphasis on mouse development, and makes these data freely available in formats appropriate for comprehensive analysis. GXD is implemented as a relational database and integrated with the Mouse Genome Database (MGD) to enable global analysis of genotype, expression and phenotype information. Interconnections with sequence databases and with… 

Figures from this paper

The Mouse Gene Expression Database (GXD)
TLDR
The Gene Expression Database (GXD) is a community resource of gene expression information for the laboratory mouse that aims to provide increasingly complete information about the expression profiles of genes in different mouse strains and mutants, thus enabling valuable insights into the molecular networks that underlie normal development and disease.
The mouse Gene Expression Database (GXD): 2007 update
TLDR
The utility of GXD has been greatly enhanced by a large increase in data content, obtained from the literature and provided by researchers doing large-scale in situ and cDNA screens, and the query and display features have been refined to make it easier for users to interrogate the data.
The mouse Gene Expression Database (GXD): 2014 update
TLDR
Since the last report, the utility of GXD has been greatly enhanced by the addition of new data and by the implementation of more powerful and versatile search and display features.
The mouse Gene Expression Database (GXD): 2011 update
The Gene Expression Database (GXD) is a community resource of mouse developmental expression information. GXD integrates different types of expression data at the transcript and protein level and
The mouse Gene Expression Database (GXD): 2019 update
TLDR
The ability of GXD to provide insights into the molecular mechanisms of development and disease has been greatly enhanced by the addition of new data and by the implementation of new web features.
GXD: a community resource of mouse Gene Expression Data
TLDR
The Gene Expression Database (GXD) is an extensive, easily searchable, and freely available database of mouse gene expression information that can provide researchers with critical insights into the functions of genes and the molecular mechanisms of development, differentiation, and disease.
The Mouse Genome Database (MGD): expanding genetic and genomic resources for the laboratory mouse
TLDR
The Mouse Genome Database is a comprehensive public database of mouse genomic, genetic and phenotypic information that represents standardized mouse nomenclature for genes and alleles, incorporates links to other genomic resources such as sequence data, and includes a variety of additional information about the laboratory mouse.
The mouse Gene Expression Database (GXD): 2017 update
TLDR
The Gene Expression Database (GXD) is an extensive and well-curated community resource of mouse developmental expression information that collects and integrates data from RNA in situ hybridization, immunohistochemistry, RT-PCR, northern blot and western blot experiments.
The Mouse Genome Database (MGD): genetic and genomic information about the laboratory mouse. The Mouse Genome Database Group
TLDR
The Mouse Genome Database (MGD) focuses on the integration of mapping, homology, polymorphism and molecular data about the laboratory mouse and is linked to other public databases that focus on additional information such as expression patterns, sequences, bibliographic details and large mapping panel data.
The gene expression database for mouse development (GXD): Putting developmental expression information at your fingertips
TLDR
The data and search tools of GXD are described; how to use the database most effectively is explained; how the research community can help in this process is described; and how to acquire, curate, and integrate developmental expression information is discussed.
...
...

References

SHOWING 1-10 OF 20 REFERENCES
The mouse gene expression database GXD
  • Ringwald, Davis, Eppig
  • Biology, Computer Science
    Seminars in cell & developmental biology
  • 1997
TLDR
The design and implementation of GXD is described and, in particular, the gene expression annotator is illustrated, an electronic system for submitting expression data to the database.
The mouse atlas and graphical gene-expression database
TLDR
This article reviews the progress that has been made in this project and describes its two major components, CD-ROMs of the 3-D reconstructions to be held on the user's computer and a gene-expression database that will be maintained at a host site, the two being linked over the internet by a complex Java-based interface for submitting data and querying the database.
A database for mouse development.
TLDR
An ongoing project between the Jackson Laboratory, the Medical Research Council, and the University of Edinburgh to establish a gene expression information resource for mouse development that would contain such information organized so that it can be readily queried.
The Genome Sequence DataBase (GSDB): improving data quality and data access
TLDR
The ultimate goal of this work is to make GSDB a more useful resource for genomic comparison studies and gene level studies by improving data quality and by providing data access capabilities that are consistent with the needs of both types of studies.
The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression.
TLDR
An effort to share resources such that the maximum amount of gene-related data is obtained with the last redundancy is described, to have the data derived from the use of common reagents placed in public databases, and to create master arrays containing a representative cDNA clone from each gene.
DNA Data Bank of Japan at work on genome sequence data
TLDR
The DNA Data Bank of Japan (DDBJ) has recently begun receiving, processing and releasing EST and genome sequence data submitted by various Japanese genome projects, and a genome information system using Java is developed.
Differential gene expression in the murine thymus assayed by quantitative hybridization of arrayed cDNA clones.
TLDR
High-throughput measurement of hybridization signatures obtained using complex probes prepared from poly(A)+ RNA and high-density cDNA colony filters is described and good correlation is observed between expression profiles determined by this method and by Northern blotting.
3-D Reconstructions for graphical databases of gene expression
TLDR
Methods for reconstructing data from serial sections of tissues are discussed and approaches to aligning adjacent sections, removing sectioning distortions and delineating the final patterns on their embryo background so as to optimize the quality of the reconstructions are discussed.
Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray
TLDR
A high-capacity system was developed to monitor the expression of many genes in parallel by means of simultaneous, two-color fluorescence hybridization, which enabled detection of rare transcripts in probe mixtures derived from 2 micrograms of total cellular messenger RNA.
...
...