GWAS Follow-up Study Discovers a Novel Genetic Signal on 10q21.2 for Atopic Dermatitis in Chinese Han Population

  title={GWAS Follow-up Study Discovers a Novel Genetic Signal on 10q21.2 for Atopic Dermatitis in Chinese Han Population},
  author={Xingjun Cai and Lu Cheng and Chong-xian Yu and Yan-Yan Wu and Ling Fang and Xiao-dong Zheng and Fusheng Zhou and Yuming Sheng and Jun Zhu and Jie Zheng and Yuan-yuan Wu and Fengli Xiao},
  journal={Frontiers in Genetics},
Atopic dermatitis (AD) is a common inflammatory skin disease with high heritability. Two susceptibility loci have been confirmed in our previous AD genome-wide association study (GWAS). To look for additional genetic factors in Chinese Han ethnicity, we performed a large-scale GWAS follow-up study. Forty-nine top single nucleotide polymorphisms (SNPs) that had never been reported previously were genotyped using Sequenom Massarray system in an independent cohort, which consist of northern… 

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