GUN4, a Regulator of Chlorophyll Synthesis and Intracellular Signaling

@article{Larkin2003GUN4AR,
  title={GUN4, a Regulator of Chlorophyll Synthesis and Intracellular Signaling},
  author={Robert M. Larkin and Jos{\'e} M. Alonso and Joseph R. Ecker and Joanne Chory},
  journal={Science},
  year={2003},
  volume={299},
  pages={902 - 906}
}
Nuclear genes control plastid differentiation in response to developmental signals, environmental signals, and retrograde signals from plastids themselves. In return, plastids emit signals that are essential for proper expression of many nuclear photosynthetic genes. Accumulation of magnesium-protoporphyrin IX (Mg-Proto), an intermediate in chlorophyll biosynthesis, is a plastid signal that represses nuclear transcription through a signaling pathway that, inArabidopsis, requires the GUN4 gene… 
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TLDR
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  • 2014
TLDR
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A ROLE FOR CHLOROPHYLL PRECURSORS IN PLASTID-TO-NUCLEUS SIGNALING
TLDR
A number of studies have indicated that proper expression of nuclear genes that encode proteins with functions related to photosynthesis is dependent on normal chloroplast development in diverse monocotyledonous and dicotylingonous genome was lost or transferred to the nucleus of the eukaryotic host.
Plastid-to-nucleus signalling.
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  • 2004
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