GUILDify: a web server for phenotypic characterization of genes through biological data integration and network-based prioritization algorithms

  title={GUILDify: a web server for phenotypic characterization of genes through biological data integration and network-based prioritization algorithms},
  author={Emre Guney and Javier Garc{\'i}a-Garc{\'i}a and Baldomero Oliva},
  volume={30 12},
SUMMARY Determining genetic factors underlying various phenotypes is hindered by the involvement of multiple genes acting cooperatively. Over the past years, disease-gene prioritization has been central to identify genes implicated in human disorders. Special attention has been paid on using physical interactions between the proteins encoded by the genes to link them with diseases. Such methods exploit the guilt-by-association principle in the protein interaction network to uncover novel… 

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