GTSE1 expression represses apoptotic signaling and confers cisplatin resistance in gastric cancer cells

@inproceedings{Subhash2015GTSE1ER,
  title={GTSE1 expression represses apoptotic signaling and confers cisplatin resistance in gastric cancer cells},
  author={Vinod Vijay Subhash and Shi Hui Tan and Woei Loon Tan and Mei Shi Yeo and Chen Xi Xie and Foong Ying Wong and Zee Ying Kiat and Robert Seng-Cheong Lim and Wei Peng Yong},
  booktitle={BMC Cancer},
  year={2015}
}
Platinum based therapy is commonly used in the treatment of advanced gastric cancer. However, resistance to chemotherapy is a major challenge that causes marked variation in individual response rate and survival rate. In this study, we aimed to identify the expression of GTSE1 and its correlation with cisplatin resistance in gastric cancer cells. Methylation profiling was carried out in tissue samples from gastric cancer patients before undergoing neoadjuvent therapy using docetaxel, cisplatin… CONTINUE READING
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Methylation profiling was carried out in tissue samples from gastric cancer patients before undergoing neoadjuvent therapy using docetaxel , cisplatin and 5FU ( DCX ) and in gastric cancer cell lines .
Methylation profiling was carried out in tissue samples from gastric cancer patients before undergoing neoadjuvent therapy using docetaxel , cisplatin and 5FU ( DCX ) and in gastric cancer cell lines .
cancer cellIs abnormal cell of diseaseStomach Carcinoma
Methylation profiling was carried out in tissue samples from gastric cancer patients before undergoing neoadjuvent therapy using docetaxel , cisplatin and 5FU ( DCX ) and in gastric cancer cell lines .
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