GTP[S] stimulates migration of electropermeabilized neutrophils via a pertussis toxin-sensitive G-protein.

Abstract

Electropermeabilized neutrophils were used to study the role of G-proteins in neutrophil migration. Rabbit neutrophils, under specific conditions, retained their ability to migrate after electropermeabilization. Introduction of guanosine-5'-[3-thio] triphosphate (GTP[S]) into the cell interior stimulated random migration and enhanced migration activated by… (More)

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