GSTT1 null genotype frequency in a Turkish population

  title={GSTT1 null genotype frequency in a Turkish population},
  author={Basbug Oke and Fahri Akbaş and Muge Aydin and Hakan Berkkan},
  journal={Archives of Toxicology},
In humans, glutathione-S-transferases (GSTs) are involved in the detoxification of xenobiotics. A deletion polymorphism in the glutathione S-transferase Theta 1 gene (GSTT1 null genotype) is associated with an increased risk of certain forms of cancer. The distribution of this polymorphism in 240 healthy individuals has been examined, using a polymerase chain reaction (PCR)-based method. The GSTT1 null genotype frequency was 20% in a Turkish Population. 

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