GSTP1 arrests bladder cancer T24 cells in G0/G1 phase and up-regulates p21 expression.

@article{Gao2014GSTP1AB,
  title={GSTP1 arrests bladder cancer T24 cells in G0/G1 phase and up-regulates p21 expression.},
  author={Li Qin Gao and You-qiang Fang and Tianyu Zhang and Bo Ge and Bing Xu and J Huang and Zhen-feng Zhang and Ning Tan},
  journal={International journal of clinical and experimental medicine},
  year={2014},
  volume={7 9},
  pages={
          2984-91
        }
}
OBJECTIVE GSTP1 over-expression was introduced into human bladder cancer T24 cells via the lentivirus system. The influence of GSTP1 on the proliferation and cell cycle of T24 cells as well as the potential mechanisms was investigated. METHODS The lentiviral vector GSTP1-pWPXL was constructed and transfected into T24 cells in the presence of Lipofectamine 2000. CCK8 assay and colony formation test were performed to explore the impact of GSTP1 on the proliferation of T24 cells. Ollowing PI… CONTINUE READING

Figures and Topics from this paper.

References

Publications referenced by this paper.
SHOWING 1-9 OF 9 REFERENCES

Involvement of cyclin-dependent kinase CDK1/CDC28 in regulation of cell cycle

  • Russian Journal of Genetics
  • 2013
VIEW 11 EXCERPTS
HIGHLY INFLUENTIAL

Cancers of the bladder.

  • The journal of the Royal Society for the Promotion of Health
  • 2004
VIEW 1 EXCERPT

Expression and significance of GST π in Human Neoplasms

ZM Liu, LY Guo, YM. Li
  • Milit Med J South China
  • 2003
VIEW 1 EXCERPT