GSTM1 and TNF-alpha gene polymorphisms and relations between blood lead and inflammatory markers in a non-occupational population.

@article{Kim2007GSTM1AT,
  title={GSTM1 and TNF-alpha gene polymorphisms and relations between blood lead and inflammatory markers in a non-occupational population.},
  author={Jin Hee Kim and Kwan-Hee Lee and Dong Ho Yoo and Daehee Kang and S Cho and Yun Chul Hong},
  journal={Mutation research},
  year={2007},
  volume={629 1},
  pages={
          32-9
        }
}
Inflammation is known to be an important underlying condition in the development of a variety of diseases. To investigate whether blood lead induces inflammatory reactions in non-occupationally exposed adults and the effects of genetic susceptibility associated with GSTM1 and TNF-alpha gene polymorphisms on this inflammatory response, we measured blood lead levels in 300 healthy university students. Total serum TNF-alpha and IL-6 levels and WBC counts were determined to evaluate the… CONTINUE READING