GSTM1 and GSTM5 Genetic Polymorphisms and Expression in Age-Related Macular Degeneration.

@article{Hunter2016GSTM1AG,
  title={GSTM1 and GSTM5 Genetic Polymorphisms and Expression in Age-Related Macular Degeneration.},
  author={Allan A. Hunter and Zeljka Smit-McBride and Rachel L. Anderson and Matthew H. Bordbari and Gui-shuang Ying and Esther Kim and S S Park and David G. Telander and Joshua L. Dunaief and Leonard M. Hjelmeland and Lawrence S. Morse},
  journal={Current eye research},
  year={2016},
  volume={41 3},
  pages={410-6}
}
PURPOSE Previously, two cytosolic antioxidant enzymes, Glutathione S-transferase Mu 1 (GSTM1) and Mu 5 (GSTM5), were reduced in retinas with age-related macular degeneration (AMD). This study compared genomic copy number variations (gCNV) of these two antioxidant enzymes in AMD versus controls. METHODS Genomic copy number (gCN) assays were performed using… CONTINUE READING