GSTM1, GSTT1 null variants, and GPX1 single nucleotide polymorphism are not associated with bladder cancer risk in Egypt.

@article{Goerlitz2011GSTM1GN,
  title={GSTM1, GSTT1 null variants, and GPX1 single nucleotide polymorphism are not associated with bladder cancer risk in Egypt.},
  author={David S. Goerlitz and Mai El Daly and Mohamed Abdel-Hamid and Doa'a A. Saleh and Lenka Goldman and Sherif El Kafrawy and Tamer Hifnawy and Sameera Ezzat and Mohamed A Abdel-Aziz and M. S. Zaghloul and Saber Rafat Ali and Hussein Mostafa Khaled and Sania Amr and Yun-Ling Zheng and Nabiel N. H. Mikhail and Christopher A. Loffredo},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2011},
  volume={20 7},
  pages={1552-4}
}
BACKGROUND Bladder cancer is the most common male malignancy in Egypt, consists predominantly of urothelial cell carcinoma (UCC) and squamous cell carcinoma (SCC), and disparities in incidence exist between men and women regardless of geographic region. Tobacco smoke exposure and Schistosoma haematobium (SH) infection and the presence of GSTM1, GSTT1, and GPX1 genotypes, as modulators of the carcinogenic effect of reactive oxidative species, were hypothesized to modify bladder cancer risk and… CONTINUE READING
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