GSK3β Signalling: Casting a Wide Net in Alzheimer’s Disease

@article{Bhat2002GSK3SC,
  title={GSK3$\beta$ Signalling: Casting a Wide Net in Alzheimer’s Disease},
  author={Ratan V Bhat and Samantha L. Budd},
  journal={Neurosignals},
  year={2002},
  volume={11},
  pages={251 - 261}
}
Glycogen synthase kinase-3β (GSK3β) is a kinase that plays a pivotal role in numerous cellular functions from modulation of microtubule dynamics and cell death. It also affects higher functions such as cognition and mood. Deregulation of GSK3β activity in the adult brain is implicated in several CNS disorders, such as affective disorders, schizophrenia, stroke and neurodegenerative diseases, such as Alzheimer’s disease (AD). In AD, GSK3β has a major role in microtubule stability by its ability… 
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