GSK3β Regulates Differentiation and Growth Arrest in Glioblastoma

Abstract

Cancers are driven by a population of cells with the stem cell properties of self-renewal and unlimited growth. As a subpopulation within the tumor mass, these cells are believed to constitute a tumor cell reservoir. Pathways controlling the renewal of normal stem cells are deregulated in cancer. The polycomb group gene Bmi1, which is required for neural… (More)
DOI: 10.1371/journal.pone.0007443

7 Figures and Tables

Topics

  • Presentations referencing similar topics