GRcalculator: an online tool for calculating and mining dose–response data

@inproceedings{Clark2017GRcalculatorAO,
  title={GRcalculator: an online tool for calculating and mining dose–response data},
  author={Nicholas A Clark and Marc Hafner and Michal Kouril and Elizabeth H Williams and Jeremy Muhlich and Marcin Pilarczyk and Mario Niepel and Peter K. Sorger and Mario Medvedovic},
  booktitle={BMC Cancer},
  year={2017}
}
Quantifying the response of cell lines to drugs or other perturbagens is the cornerstone of pre-clinical drug development and pharmacogenomics as well as a means to study factors that contribute to sensitivity and resistance. In dividing cells, traditional metrics derived from dose–response curves such as IC 50 , AUC, and E max , are confounded by the… CONTINUE READING