GRO family chemokines are specialized for monocyte arrest from flow.

@article{Smith2005GROFC,
  title={GRO family chemokines are specialized for monocyte arrest from flow.},
  author={David F. Smith and Elena Galkina and Klaus Ley and Yuqing Huo},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2005},
  volume={289 5},
  pages={H1976-84}
}
Chemokines participate in various processes of monocyte recruitment including monocyte arrest and migration. Our group and others have demonstrated that growth-related oncogene (GRO)-alpha (CXCL1) can support monocyte arrest in models of inflammation. Here we employed a parallel plate-flow chamber and Transwell reconstitution assay to test whether GRO family chemokines were sufficient for Mono Mac 6 (a human monocytic cell line) and isolated human monocyte recruitment. Our study shows that 1… CONTINUE READING

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