GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states

Abstract

Transcription factor binding, chromatin modifications and large scale chromatin re-organization underlie progressive, irreversible cell lineage commitments and differentiation. We know little, however, about chromatin changes as cells enter transient, reversible states such as migration. Here we demonstrate that when human progenitor keratinocytes either… (More)
DOI: 10.1371/journal.pgen.1006745

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