GRGDS-Functionalized Poly(lactide)-graft-poly(ethylene glycol) Copolymers: Combining Thiol-Ene Chemistry with Staudinger Ligation.

@article{Borchmann2013GRGDSFunctionalizedPG,
  title={GRGDS-Functionalized Poly(lactide)-graft-poly(ethylene glycol) Copolymers: Combining Thiol-Ene Chemistry with Staudinger Ligation.},
  author={Dorothee E. Borchmann and Niels ten Brummelhuis and Marcus Weck},
  journal={Macromolecules},
  year={2013},
  volume={46 11},
  pages={4426-4431}
}
A tri(ethylene glycol)-containing lactide analogue was synthesized via thiol-ene chemistry between a bi-functional triethylene glycol and allyl lactide. Subsequent tin-octoate-catalyzed ring-opening polymerization yielded well-defined poly(lactide)-graft-poly(ethylene glycol) copolymers with molecular weights of 6000 g/mol and polydispersity indices of 1.6… CONTINUE READING