GPIIb (CD41) integrin is expressed on mast cells and influences their adhesion properties.

@article{Berlanga2005GPIIbI,
  title={GPIIb (CD41) integrin is expressed on mast cells and influences their adhesion properties.},
  author={Oscar Berlanga and Nikla E. Emambokus and Jon Frampton},
  journal={Experimental hematology},
  year={2005},
  volume={33 4},
  pages={403-12}
}
OBJECTIVES GPIIb integrin expression has been found on platelets and megakaryocytes, and more recently on immature hematopoietic progenitors. We set out to investigate expression of GPIIb in other hematopoietic cell lineages and, having detected it on mast cells, aimed to determine what possible role it might perform. METHODS We have made use of cultured human and murine bone marrow mast cells (BMMC) in order to characterize the expression of GPIIb. Further, BMMC cultures from wild type and… CONTINUE READING

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