GPCRs of adrenal chromaffin cells & catecholamines: The plot thickens.

@article{Lymperopoulos2016GPCRsOA,
  title={GPCRs of adrenal chromaffin cells & catecholamines: The plot thickens.},
  author={Anastasios Lymperopoulos and Ava Brill and Katie A McCrink},
  journal={The international journal of biochemistry & cell biology},
  year={2016},
  volume={77 Pt B},
  pages={213-9}
}
The circulating catecholamines (CAs) epinephrine (Epi) and norepinephrine (NE) derive from two major sources in the whole organism: the sympathetic nerve endings, which release NE on effector organs, and the chromaffin cells of the adrenal medulla, which are cells that synthesize, store and release Epi (mainly) and NE. All of the Epi in the body and a significant amount of circulating NE derive from the adrenal medulla. The secretion of CAs from adrenal chromaffin cells is regulated in a… CONTINUE READING