GPCR photopharmacology

  title={GPCR photopharmacology},
  author={Maria Ricart-Ortega and J. Font and A. Llebaria},
  journal={Molecular and Cellular Endocrinology},
  • Maria Ricart-Ortega, J. Font, A. Llebaria
  • Published 2019
  • Medicine
  • Molecular and Cellular Endocrinology
  • New technologies for spatial and temporal remote control of G protein-coupled receptors (GPCRs) are necessary to unravel the complexity of GPCR signalling in cells, tissues and living organisms. An effective approach, recently developed, consists on the design of light-operated ligands whereby light-dependent GPCR activity regulation can be achieved. In this context, the use of light provides an advantage as it combines safety, easy delivery, high resolution and it does not interfere with most… CONTINUE READING

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