GP130 cytokines and bone remodelling in health and disease.

@article{Sims2010GP130CA,
  title={GP130 cytokines and bone remodelling in health and disease.},
  author={Natalie A Sims and Nicole C. Walsh},
  journal={BMB reports},
  year={2010},
  volume={43 8},
  pages={513-23}
}
Cytokines that bind to and signal through the gp130 co-receptor subunit include interleukin (IL)-6, IL-11, oncostatin M (OSM), leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), and ciliary neutrophic factor (CNTF). Apart from contributing to inflammation, gp130 signalling cytokines also function in the maintenance of bone homeostasis. Expression of each of these cytokines and their ligand-specific receptors is observed in bone and joint cells, and bone-active hormones and inflammatory… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 45 extracted citations

Similar Papers

Loading similar papers…