GM-CSF ameliorates microvascular barrier integrity via pericyte-derived Ang-1 in wound healing.

@article{Yan2017GMCSFAM,
  title={GM-CSF ameliorates microvascular barrier integrity via pericyte-derived Ang-1 in wound healing.},
  author={Min Yan and Yange Hu and Min Yao and Shisan S. Bao and Yong Fang},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  year={2017},
  volume={25 6},
  pages={
          933-943
        }
}
Skin wound healing involves complex coordinated interactions of cells, tissues, and mediators. Maintaining microvascular barrier integrity is one of the key events for endothelial homeostasis during wound healing. Vasodilation is observed after vasoconstriction, which causes blood vessels to become porous, facilitates leukocyte infiltration and aids angiogenesis at the wound-area, postinjury. Eventually, vessel integrity has to be reestablished for vascular maturation. Numerous studies have… CONTINUE READING