GM-CSF: a role in immune and inflammatory reactions in the intestine.

  title={GM-CSF: a role in immune and inflammatory reactions in the intestine.},
  author={Laia Egea and Yoshihiro Hirata and Martin F. Kagnoff},
  journal={Expert review of gastroenterology & hepatology},
  volume={4 6},
Granulocyte macrophage colony-stimulating factor (GM-CSF) is a cytokine that promotes myeloid cell development and maturation, and dendritic cell differentiation and survival in vitro. Growing evidence supports the notion that GM-CSF has a major role in some inflammatory and autoimmune reactions and in the host's response to pulmonary infection, but few studies have addressed its functions and importance in the GI tract. Recent studies demonstrated that administration of GM-CSF can result in… CONTINUE READING
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