GLUT2 mutations, translocation, and receptor function in diet sugar managing.

@article{Leturque2009GLUT2MT,
  title={GLUT2 mutations, translocation, and receptor function in diet sugar managing.},
  author={Armelle Leturque and {\'E}dith Brot-Laroche and Maude Le Gall},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2009},
  volume={296 5},
  pages={E985-92}
}
Cloned 20 years ago, GLUT2 is a facilitative glucose transporter in the liver, pancreas, intestine, kidney, and brain. It ensures large bidirectional fluxes of glucose in and out the cell due to its low affinity and high capacity. It also transports other dietary sugars, such as fructose and galactose, within the range of physiological concentrations. Sugars and hormones regulate its gene expression. The contribution of GLUT2 to human metabolic diseases previously appeared modest. However, in… CONTINUE READING
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