GLUT2 in pancreatic and extra-pancreatic gluco-detection (review).

  title={GLUT2 in pancreatic and extra-pancreatic gluco-detection (review).},
  author={Bernard Thorens},
  journal={Molecular membrane biology},
  volume={18 4},
Detection of variations in blood glucose concentrations by pancreatic beta-cells and a subsequent appropriate secretion of insulin are key events in the control of glucose homeostasis. Because a decreased capability to sense glycemic changes is a hallmark of type 2 diabetes, the glucose signalling pathway leading to insulin secretion in pancreatic beta-cells has been extensively studied. This signalling mechanism depends on glucose metabolism and requires the presence of specific molecules such… CONTINUE READING


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