GLUCOSE INTOLERANCE IN HYPERTENSIVE PATIENTS TREATED WITH DIURETICS; A FOURTEEN-YEAR FOLLOW-UP

@article{Murphy1982GLUCOSEII,
  title={GLUCOSE INTOLERANCE IN HYPERTENSIVE PATIENTS TREATED WITH DIURETICS; A FOURTEEN-YEAR FOLLOW-UP},
  author={Michael B. Murphy and Eva M. Kohner and PeterJ. Lewis and B Schumer and Colin T. Dollery},
  journal={The Lancet},
  year={1982},
  volume={320},
  pages={1293-1295}
}
Abstract Glucose tolerance was studied prospectively in thirty-four hypertensive patients treated with oral thiazide diuretics without interruption for 14 years. Standard oral glucose tolerance tests were carried out before treatment and after 1, 6, and 14 years. Mean fasting blood glucose increased from 4·7±0·6 to 6·0±2·3 mmol/l and the 2 h value rose from 5·5+1·9 to 8·0±4·7 mmol/l after 14 years. Withdrawal of thiazide therapy for 7 months in ten of the patients resulted in mean reductions of… Expand
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