GLU-27 variant of beta2-adrenergic receptor polymorphisms is an independent risk factor for coronary atherosclerotic disease.

@article{Barbato2007GLU27VO,
  title={GLU-27 variant of beta2-adrenergic receptor polymorphisms is an independent risk factor for coronary atherosclerotic disease.},
  author={Emanuele Barbato and Alexandre Berger and Leen Delrue and Frederik Van Durme and Ganesh Manoharan and Tim Boussy and Guy R. Heyndrickx and Bernard De Bruyne and Quirino Ciampi and Marc Vanderheyden and William Wijns and Jozef J. Bartunek},
  journal={Atherosclerosis},
  year={2007},
  volume={194 2},
  pages={e80-6}
}
OBJECTIVE Arg16Gly and Gln27Glu polymorphism of beta(2)-adrenergic receptors (beta 2AR) have been associated with several risk factors for coronary atherosclerotic disease (CAD). Nevertheless, conflicting data have been reported concerning their influence on CAD and cardiovascular clinical events. AIM To investigate whether (a) beta 2AR polymorphisms are associated with CAD; and (b) the potential impact, if any, of these polymorphisms on cardiovascular clinical events in patients presenting… CONTINUE READING
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