GLP-1 secretion is stimulated by 1,10-phenanthroline via colocalized T2R5 signal transduction in human enteroendocrine L cell.

@article{Park2015GLP1SI,
  title={GLP-1 secretion is stimulated by 1,10-phenanthroline via colocalized T2R5 signal transduction in human enteroendocrine L cell.},
  author={Jiyoung Park and Ki-Suk Kim and Kang-Hoon Kim and In-Seung Lee and Hyeon-soo Jeong and Yumi Kim and Hyeung-Jin Jang},
  journal={Biochemical and biophysical research communications},
  year={2015},
  volume={468 1-2},
  pages={306-11}
}
Glucagon-like peptide-1 (GLP-1) hormone is known to regulate blood glucose by an insulinotropic effect and increases proliferation as and also prevents apoptosis of pancreatic β cells. We know that GLP-1 is secreted by nutrients such as fatty acids and sweet compounds but also bitter compounds via stimulation of G-protein coupled receptors (GPCRs) in the… CONTINUE READING