GLP-1 receptor activation modulates appetite- and reward-related brain areas in humans.


Gut-derived hormones, such as GLP-1, have been proposed to relay information to the brain to regulate appetite. GLP-1 receptor agonists, currently used for the treatment of type 2 diabetes (T2DM), improve glycemic control and stimulate satiety, leading to decreases in food intake and body weight. We hypothesized that food intake reduction after GLP-1… (More)
DOI: 10.2337/db14-0849

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