GHRH excess and blockade in X-LAG syndrome.

@article{Daly2016GHRHEA,
  title={GHRH excess and blockade in X-LAG syndrome.},
  author={Adrian F Daly and Philippe A Lysy and C{\'e}line Desfilles and Liliya Rostomyan and Amira Mohamed Osman Mohamed and Jean-Hubert D Caberg and V{\'e}ronique Raverot and Emilie Castermans and Etienne Marbaix and Dominique Maiter and Chlo{\'e} Brunelle and Giampaolo Trivellin and Constantine A. Stratakis and Vincent Bours and Christian Raftopoulos and V{\'e}ronique Beauloye and Anne Barlier and Albert M. Beckers},
  journal={Endocrine-related cancer},
  year={2016},
  volume={23 3},
  pages={161-70}
}
X-linked acrogigantism (X-LAG) syndrome is a newly described form of inheritable pituitary gigantism that begins in early childhood and is usually associated with markedly elevated GH and prolactin secretion by mixed pituitary adenomas/hyperplasia. Microduplications on chromosome Xq26.3 including the GPR101 gene cause X-LAG syndrome. In individual cases random GHRH levels have been elevated. We performed a series of hormonal profiles in a young female sporadic X-LAG syndrome patient and… CONTINUE READING