GH in combination with bisphosphonate treatment in osteogenesis imperfecta.

@article{Antoniazzi2010GHIC,
  title={GH in combination with bisphosphonate treatment in osteogenesis imperfecta.},
  author={Franco Antoniazzi and Elena Monti and Giacomo Venturi and Roberto De Franceschi and Francesco Doro and D Gatti and Giorgio Zamboni and Luciano Tat{\`o}},
  journal={European journal of endocrinology},
  year={2010},
  volume={163 3},
  pages={479-87}
}
OBJECTIVE To verify the effects of bisphosphonates (Bps) in combination with recombinant human GH (rGH) in pediatric osteogenesis imperfecta (OI) patients; we focused on possible improvement of bone mineral density (BMD), projected bone areas, growth velocity, and fractures risk. DESIGN A randomized controlled 1-year clinical trial on 30 prepubertal children (M:F=14:16) affected by OI (type I, IV, and III) being treated with neridronate. METHODS Following an observational period of 12… CONTINUE READING
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