GH but not IGF-I or insulin increases lipoprotein lipase activity in muscle tissues of hypophysectomised rats.

@article{Oscarsson1999GHBN,
  title={GH but not IGF-I or insulin increases lipoprotein lipase activity in muscle tissues of hypophysectomised rats.},
  author={Jan Oscarsson and Malin Ottosson and K Vikman-Adolfsson and Fredrik Frick and Sven Enerb{\"a}ck and Hans 0. Lithell and Staffan Ed{\'e}n},
  journal={The Journal of endocrinology},
  year={1999},
  volume={160 2},
  pages={247-55}
}
Changes in GH secretion are associated with changes in serum lipoproteins, utilisation of fuels and body composition. Since lipoprotein lipase (LPL) is a key enzyme in the regulation of lipid and lipoprotein metabolism, changes in LPL activity may contribute to these effects of GH. The present study was undertaken to investigate the role of GH and the GH-dependent growth factor, IGF-I, in the regulation of LPL in heart, skeletal muscle and adipose tissue. Female rats were hypophysectomised at… CONTINUE READING
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