GGAing ubiquitin to the endosome

  • M. Babst
  • Published 2004 in Nature Cell Biology


Delivery of transmembrane proteins to the lumen of the lysosome is mediated by their ubiquitination, and subsequent recognition and sorting at the endosome. A new group of ubiquitin-binding proteins has now been identified that seem to function in the delivery of ubiquitinated cargo both from the cell surface and the trans-Golgi network (TGN) to the… (More)
DOI: 10.1038/ncb0304-175


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