GFAP, FVIII/RAg, Laminin, and fibronectin in gliosarcomas: An immunohistochemical study

  title={GFAP, FVIII/RAg, Laminin, and fibronectin in gliosarcomas: An immunohistochemical study},
  author={Davide Schiffer and Maria Teresa Giordana and Alessandro Mauro and Antonio Migheli},
  journal={Acta Neuropathologica},
GFAP, Factor VIII/RAg, laminin, and fibronectin were immunohistochemically investigated in 15 glioblastomas and 15 gliosarcomas. GFAP was found variably positive in the glial areas. F VIII/RAg characterizes the endothelial cells and in gliosarcomas suggests the origin of the sarcomatous component from the endothelial proliferations. Laminin separates the two components and characterizes the inner and the outer basement membranes in the vessels. It is multiplied and thickened in endothelial… CONTINUE READING


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Publications referenced by this paper.
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Capillary endothelial cell cultures: phenotypic modulation by matrix components

  • JA Madri, SK Williams, T Wyatt, C Mezzio
  • J Cell Biol
  • 1983
1 Excerpt

Collagenase in the immunohistochemical demonstration of laminin, fibronecfin and F VIII/RAg in the nervous tissue after fixation

  • A Mauro, A Bertolotto, +4 authors D Schiffer
  • Histochemistry (in press)
  • 1983
1 Excerpt

Basic concepts and experimental approaches on cellular differentiation and anaplasia in neuroepitheliaI tumors

  • LJ Rubinstein
  • Eur Course Neurosurg,
  • 1982
2 Excerpts

Isolation and characterization of the cells of the cerebral microvessels

  • LE De Bault
  • Advances in cellular neurobiology,
  • 1982

Specificity and sensitivity ofimmunohistochemical detection of F VIII/RAg in formalin-fixed paraffin-embedded tissue

  • RD McComb, RJ Trevor, SV Pizzo, DD Bigner
  • J Histochem Cytochem 30:
  • 1982
1 Excerpt

Extracellular matrix

  • ED Hay
  • J Cell Biol
  • 1981
1 Excerpt

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