GFAJ-1 Is an Arsenate-Resistant, Phosphate-Dependent Organism

@article{Erb2012GFAJ1IA,
  title={GFAJ-1 Is an Arsenate-Resistant, Phosphate-Dependent Organism},
  author={T. Erb and P. Kiefer and B. Hattendorf and D. G{\"u}nther and J. Vorholt},
  journal={Science},
  year={2012},
  volume={337},
  pages={467 - 470}
}
Resisting Arsenic The discovery of a bacterium living in the extreme conditions of Mono Lake, California, created a major controversy because it was claimed to be able to grow solely on arsenic and could substitute arsenate for phosphate in its key macromolecules, including DNA. Working with the same Halomonas spp. bacterium, known as GFAJ-1, and ultrapure reagents, Erb et al. (p. 467) found that the bacterium needed a low level of phosphate (1.6 µM) to grow at all. Rather than significant… Expand
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  • 25
  • PDF
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  • 18
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5
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References

SHOWING 1-10 OF 15 REFERENCES
A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus
  • 409
  • PDF
Effect of arsenate on inorganic phosphate transport in Escherichia coli.
  • 120
  • PDF
Sugar-arsenate esters: thermodynamics and biochemical behavior.
  • R. Lagunas
  • Chemistry, Medicine
  • Archives of biochemistry and biophysics
  • 1980
  • 35
...
1
2
...