• DOI:10.1126/science.1218455
Corpus ID: 20229329

GFAJ-1 Is an Arsenate-Resistant, Phosphate-Dependent Organism

@article{Erb2012GFAJ1IA,
  title={GFAJ-1 Is an Arsenate-Resistant, Phosphate-Dependent Organism},
  author={T. Erb and P. Kiefer and B. Hattendorf and D. G{\"u}nther and J. Vorholt},
  journal={Science},
  year={2012},
  volume={337},
  pages={467 - 470}
}

• T. Erb, P. Kiefer, +2 authors J. Vorholt
• Published 2012
• Biology, Medicine
• Science

Resisting Arsenic The discovery of a bacterium living in the extreme conditions of Mono Lake, California, created a major controversy because it was claimed to be able to grow solely on arsenic and could substitute arsenate for phosphate in its key macromolecules, including DNA. Working with the same Halomonas spp. bacterium, known as GFAJ-1, and ultrapure reagents, Erb et al. (p. 467) found that the bacterium needed a low level of phosphate (1.6 µM) to grow at all. Rather than significant… Expand

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