GENOCOP algorithm and hierarchical grid transformation for image warping of two dimensional gel eletrophoretic maps.

@article{Marengo2012GENOCOPAA,
  title={GENOCOP algorithm and hierarchical grid transformation for image warping of two dimensional gel eletrophoretic maps.},
  author={Emilio Marengo and Marina Cocchi and Marco Demartini and Elisa Robotti and Daniela Cecconi and Giorgio Calabrese},
  journal={Molecular bioSystems},
  year={2012},
  volume={8 4},
  pages={975-84}
}
Hierarchical grid transformation is a powerful approach to SDS 2DPAGE maps warping. The hierarchy of the warping transformation is able to model both global and local deformations of the gels and the algorithm can be stopped when a certain degree of accuracy in the image alignment is obtained. The numerical optimization of the position of the nodes of the grid that are responsible for the image warping is a multivariate task that can be solved efficiently using Genetic Algorithms. The use of… CONTINUE READING