GEM-loaded magnetic albumin nanospheres modified with cetuximab for simultaneous targeting, magnetic resonance imaging, and double-targeted thermochemotherapy of pancreatic cancer cells

@inproceedings{Wang2015GEMloadedMA,
  title={GEM-loaded magnetic albumin nanospheres modified with cetuximab for simultaneous targeting, magnetic resonance imaging, and double-targeted thermochemotherapy of pancreatic cancer cells},
  author={Ling Wang and Yanli An and Chenyan Yuan and Hao Chi Zhang and Chen Liang and Fengan Ding and Qi Xin Gao and Dongsheng Zhang},
  booktitle={International journal of nanomedicine},
  year={2015}
}
BACKGROUND Targeted delivery is a promising strategy to improve the diagnostic imaging and therapeutic effect of cancers. In this paper, novel cetuximab (C225)-conjugated, gemcitabine (GEM)-containing magnetic albumin nanospheres (C225-GEM/MANs) were fabricated and applied as a theranostic nanocarrier to conduct simultaneous targeting, magnetic resonance imaging (MRI), and double-targeted thermochemotherapy against pancreatic cancer cells. METHODS Fe3O4 nanoparticles (NPs) and GEM co-loaded… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 48 REFERENCES

In vitro evaluation of doxorubicin - incorporated magnetic albumin nanospheres

R Yang, Y An, +3 authors Q Tang
  • Chem Biol Drug Des
  • 2014