GEANT4 Monte Carlo simulations for virtual clinical trials in breast X-ray imaging: Proof of concept.

@article{diFranco2020GEANT4MC,
  title={GEANT4 Monte Carlo simulations for virtual clinical trials in breast X-ray imaging: Proof of concept.},
  author={Francesca di Franco and Antonio Sarno and Giovanni Mettivier and A.M. Hernandez and Kristina Bliznakova and J Boone and Paolo Russo},
  journal={Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics},
  year={2020},
  volume={74},
  pages={
          133-142
        }
}
  • F. di Franco, A. Sarno, P. Russo
  • Published 26 May 2020
  • Medicine, Physics
  • Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics
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13 Citations
Background Citations
1
Methods Citations
2

13 Citations

Virtual Clinical Trials in 2D and 3D X-ray Breast Imaging and Dosimetry: Comparison of CPU-Based and GPU-Based Monte Carlo Codes
TLDR
This work aims to compare three different platforms for breast VCT studies, to develop real-time virtual DM, DBT and BCT examinations, where the in-silico image acquisition process takes a computational time comparable to that typical of a corresponding real clinical examination.
Dataset of patient-derived digital breast phantoms for in-silico studies in breast computed tomography, digital breast tomosynthesis and digital mammography.
TLDR
The dataset developed within the INFN AGATA project will be used for developing a platform for virtual clinical trials in x-ray breast imaging and dosimetry and will represent a valid support for introducing new breast models for dose estimates in 2D and 3D x-rays Breast imaging and as models for manufacturing anthropomorphic physical phantoms.
Empirical detector model for simulated breast exams with a dedicated breast CT scanner
TLDR
The model for the case of cone-beam computed tomography dedicated to the breast that uses a indirect conversion flat-panel detector for direct conversion a-Se detectors used in digital mammography and digital breast tomosynthesis is introduced.
Voxelized Breast Phantoms for Dosimetry in Mammography
TLDR
A new heterogeneous digital breast model is proposed, involving a voxelized approach and disengaging from the concept of homogeneous phantom, to evaluate mean glandular dose discrepancies with the traditional model which is adopted in clinic for decades.
Technical Note: MC-GPU breast dosimetry validations with other Monte Carlo codes and Phase Space File implementation.
TLDR
The results indicate that MC-GPU code is suitable for breast dosimetric studies for different x-ray breast imaging modalities, with the advantage of a high performance derived from GPUs.
The advent of anthropomorphic three-dimensional breast phantoms for X-ray imaging.
  • K. Bliznakova
  • Medicine
    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics
  • 2020
Simulated sensor characterization for virtual clinical trials in mammography and digital breast tomosynthesis
Virtual clinical trials in X-ray breast imaging permit to compare different technical solutions and imaging modalities at reduced costs, involved personnel, reduced times and reduced radiation risks…
Comparisons of glandular breast dose between digital mammography, tomosynthesis and breast CT based on anthropomorphic patient-derived breast phantoms.
Breast glandularity and mean glandular dose assessment using a deep learning framework: Virtual patients study.
  • Rodrigo T Massera, A. Tomal
  • Medicine, Physics
    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics
  • 2021
Normalized glandular dose coefficients for digital breast tomosynthesis systems with a homogeneous breast model
TLDR
The DgNDBT coefficients are proposed as unique conversion coefficients for MGD estimates, in place of dose conversion coefficients in mammography (DgNDM or c, g, s triad as proposed in worldwide quality assurance protocols) used together with the T correction factor.
...
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    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics
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