GDNF-pretreatment enhances the survival of neural stem cells following transplantation in a rat model of Parkinson's disease.


Cell transplantation has been shown to be an effective therapy for central nervous system disorders in animal models. Improving the efficacy of cell transplantation depends critically on improving grafted cell survival. We investigated whether glial cell line-derived neurotrophic factor (GDNF)-pretreatment of neural stem cells (NSCs) enhanced grafted cell… (More)
DOI: 10.1016/j.neures.2011.05.019