GDNF and BDNF alter the expression of neuronal NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion in adult rats.

@article{Wu2003GDNFAB,
  title={GDNF and BDNF alter the expression of neuronal NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion in adult rats.},
  author={Wutian Wu and Linxi Li and L M Shirley Yick and Hong Chai and Yuanyun Xie and Yi Yang and David M. Prevette and Ronald William Oppenheim},
  journal={Journal of neurotrauma},
  year={2003},
  volume={20 6},
  pages={603-12}
}
In the present study, we examined the effects of glial cell line-derived neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF), ciliary neurotrophic factor (CNTF), and insulin growth factor (IGF-1) on adult motoneuron survival following spinal root avulsion. The expression of neuronal nitric oxide synthase (nNOS), c-Jun, and the low-affinity… CONTINUE READING