GBV-C: State of the Art and Future Prospects

@article{Giret2012GBVCSO,
  title={GBV-C: State of the Art and Future Prospects},
  author={Mar{\'i}a Teresa Maidana Giret and Esper Georges Kall{\'a}s},
  journal={Current HIV/AIDS Reports},
  year={2012},
  volume={9},
  pages={26-33}
}
The GB virus C is a common non-pathogenic virus, member of the Flaviviridae family with worldwide distribution. Favorable clinical course and reduced mortality among HIV-infected patients was demonstrated by several studies with patients co-infected with the GB virus C (GBV-C). This potential benefit of GBV-C has been demonstrated in the pre-HAART and post-HAART eras; however, this effect was not observed in all studies and the discrepancy may be due to changes during the course of HIV… 
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24 Citations

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Voluntary super-infection of a subject having HIV/AIDS with a virus (GBV-C) is presented, which has been shown to counter, suppress or eradicate the agent responsible for the severe disease.
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It is revealed that HPgV-1 genotype 7 groups exhibited significantly lower HIV-1 viral load and higher CD4+ cell counts, which suggests that HPGV- 1 genotypes 7 may be associated with a better progression of HIV- 1 disease.
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GMT-C and TTV infections are common in patients undergoing hemodialysis in Yogyakarta, Indonesia, and transmission is likely to be nosocomial in the case of GBV-C infection.
Impact of GB virus C viraemia on clinical outcome in HIV‐1‐infected patients: a 20‐year follow‐up study
TLDR
Evaluated patterns in long‐term mortality and morbidity outcomes in patients attending the Hannover Medical School in 2001 found the introduction of antiretroviral therapy (ART) had an impact on the perceived benefits of GBV‐C viraemia.
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The results indicate that HPgV-2 is a novel bloodborne infectious virus of humans and likely transmitted via the parenteral route.
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