GBF1: A novel Golgi-associated BFA-resistant guanine nucleotide exchange factor that displays specificity for ADP-ribosylation factor 5.

Abstract

Expression cloning from a cDNA library prepared from a mutant CHO cell line with Golgi-specific resistance to Brefeldin A (BFA) identified a novel 206-kD protein with a Sec7 domain termed GBF1 for Golgi BFA resistance factor 1. Overexpression of GBF1 allowed transfected cells to maintain normal Golgi morphology and grow in the presence of BFA. Golgi… (More)

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@article{Claude1999GBF1AN, title={GBF1: A novel Golgi-associated BFA-resistant guanine nucleotide exchange factor that displays specificity for ADP-ribosylation factor 5.}, author={Andrew K Claude and Binsheng Zhao and C E Kuziemsky and Serge Dahan and Suzanne Berger and Jeff Yan and Adrian D. Armold and Eric Sullivan and Pierre Melancon}, journal={The Journal of cell biology}, year={1999}, volume={146 1}, pages={71-84} }