GBF-dependent family genes morphologically suppress the partially active Dictyostelium STATa strain

@article{Shimada2008GBFdependentFG,
  title={GBF-dependent family genes morphologically suppress the partially active Dictyostelium STATa strain},
  author={Nao Shimada and Naoko Kanno-Tanabe and Kakeru Minemura and Takefumi Kawata},
  journal={Development Genes and Evolution},
  year={2008},
  volume={218},
  pages={55-68}
}
Transcription factor Dd-STATa, a functional Dictyostelium homologue of metazoan signal transducers and activators of transcription proteins, is necessary for culmination during development. We have isolated more than 18 putative multicopy suppressors of Dd-STATa using genetic screening. One was hssA gene, whose expression is known to be G-box-binding-factor-dependent and which was specific to prestalk A (pstA) cells, where Dd-STATa is activated. Also, hssA mRNA was expressed in pstA cells in… CONTINUE READING
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