GB virus type C envelope protein E2 elicits antibodies that react with a cellular antigen on HIV-1 particles and neutralize diverse HIV-1 isolates.

Abstract

Broadly neutralizing Abs to HIV-1 are well described; however, identification of Ags that elicit these Abs has proven difficult. Persistent infection with GB virus type C (GBV-C) is associated with prolonged survival in HIV-1-infected individuals, and among those without HIV-1 viremia, the presence of Ab to GBV-C glycoprotein E2 is also associated with… (More)
DOI: 10.4049/jimmunol.1001980

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@article{Mohr2010GBVT, title={GB virus type C envelope protein E2 elicits antibodies that react with a cellular antigen on HIV-1 particles and neutralize diverse HIV-1 isolates.}, author={Emma L Mohr and Jinhua Xiang and James H. McLinden and Thomas M. Kaufman and Qing Chang and David C. Montefiori and Donna Klinzman and Jack T. Stapleton}, journal={Journal of immunology}, year={2010}, volume={185 7}, pages={4496-505} }